Outcomes of Late-Onset Bleb-Related Endophthalmitis Treated with Pars Plana Vitrectomy
Table 1
Characteristics of cases.
(a)
Case
Gender
Age (years)
Type of glaucoma
PSITE (days)
HPB (+/−)
Bacteria/location
BCVA before infection ( value)
BCVA after surgery ( value)
IOP before BRE (mmHg)
IOP after surgery (mmHg)
1
Male
62
SOAG (Uveitis)
0
+
Enterococcus faecalis/V
0.10
3
8
12
2
Female
56
SOAG
2
+
S. pneumoniae/C
0.70
5
5
0
3
Male
73
POAG
2
+
S. pneumoniae/V
0.52
5
6
7
4
Male
53
SOAG (Uveitis)
2
+
Group A Str/C, A
−0.08
1.70
6
18
5
Female
68
SOAG (steroid)
3
+
Unidentifiable Str/I GPR/C, V
0.40
0.40
14
16
6
Female
81
Congenital
7
+
S. mitis/A
1.52
5
7
2
7
Female
40
Congenital
0
No growth
0.22
0.70
15
30
8
Male
41
POAG
0
S. epidermidis/A
0
0
10
11
9
Female
62
SOAG
1
No growth
0.52
0.70
9
11
10
Female
30
Congenital
3
No growth
0.15
0.82
11
22
11
Male
53
POAG
4
GPR/C
−0.08
0.30
10
10
(b)
Case
Follow-up periods (years)
Period from LET to BRE (years)
General complications
Bleb leakage
Intraoperative laser treatment
Intravitreously administrated antibiotics during surgery
Antibiotic eye drops after surgery
Systemic antibiotics after PPV
Phakia, IOL, and aphakia
1
4.9
11
—
+
Vancomycin/ceftazidime
Levofloxacin/cefmenoxime
—
Phakia
2
5.0
2
Sjögren’s syndrome
+
+
Vancomycin/ceftazidime
Levofloxacin/cefmenoxime
—
Phakia
3
5.8
5
—
+
Vancomycin/ceftazidime
Levofloxacin/cefmenoxime
—
IOL
4
8.6
3
—
+
+
Imipenem
Sulpelin/erythromycin/ tobramycin
—
IOL
5
3.8
6
Dermatomyositis
+
Vancomycin/ceftazidime
Levofloxacin
Imipenem
IOL
6
0.2
16
Axenfeld-Rieger syndrome
+
Ceftazidime
Levofloxacin/cefmenoxime/ tobramycin/vancomycin
Imipenem/ ceftazidime
Phakia
7
0.7
7
—
Vancomycin/ceftazidime
Levofloxacin/cefmenoxime
Imipenem
Phakia
8
1.3
6
—
+
Vancomycin/ceftazidime
Gatifloxacin/cefmenoxime
—
IOL
9
3.0
1
Diabetic mellitus
+
Vancomycin/ceftazidime
Gatifloxacin/cefmenoxime/ vancomycin
Imipenem
IOL
10
2.6
17
—
+
Vancomycin/ceftazidime
Gatifloxacin/cefmenoxime
Flomoxef
Aphakia
11
0.8
9
—
+
+
Vancomycin/ceftazidime
Levofloxacin/cefmenoxime
—
Phakia
SOAG = secondary open angle glaucoma, POAG = primary open angle glaucoma, PSITE = the periods from starting symptom to initiation of treatment for endophthalmitis, HPB = highly pathogenic bacteria, V = vitreous specimen, C = conjunctival specimen, A = anterior chamber’s specimen, I = specimen of removed intraocular lens, BCVA = best corrected visual acuity, IOP = intraocular pressure, BRE = bleb-related endophthalmitis, S. pneumoniae = Streptococcus pneumoniae, group A Str = group A Streptococcus, S. mitis = Streptococcus mitis, unidentifiable Str = unidentifiable Streptococcus, group G Str = group G Streptococcus, S. epidermidis = Staphylococcus epidermidis, LET = trabeculectomy, PPV = pars plana vitrectomy, and IOL = intraocular lens.