Clinical Study

Outcomes of Late-Onset Bleb-Related Endophthalmitis Treated with Pars Plana Vitrectomy

Table 1

Characteristics of cases.
(a)

CaseGenderAge
(years)
Type of glaucomaPSITE
(days)
HPB
(+/−)
Bacteria/locationBCVA before infection
( value)
BCVA after surgery
( value)
IOP before BRE
(mmHg)
IOP after surgery
(mmHg)

1Male62SOAG (Uveitis)0+Enterococcus faecalis/V0.103812
2Female56SOAG2+S. pneumoniae/C0.70550
3Male73POAG2+S. pneumoniae/V0.52567
4Male53SOAG (Uveitis)2+Group A Str/C, A−0.081.70618
5Female68SOAG (steroid)3+Unidentifiable Str/I
GPR/C, V
0.400.401416
6Female81Congenital7+S. mitis/A1.52572
7Female40Congenital0No growth0.220.701530
8Male41POAG0S. epidermidis/A001011
9Female62SOAG1No growth0.520.70911
10Female30Congenital3No growth0.150.821122
11Male53POAG4GPR/C−0.080.301010

(b)

CaseFollow-up periods (years)Period from LET to BRE (years)General complicationsBleb leakageIntraoperative laser treatmentIntravitreously administrated antibiotics during surgeryAntibiotic eye drops after surgerySystemic antibiotics after PPVPhakia, IOL, and aphakia

14.911+Vancomycin/ceftazidimeLevofloxacin/cefmenoximePhakia
25.02 Sjögren’s syndrome++Vancomycin/ceftazidimeLevofloxacin/cefmenoximePhakia
35.85+Vancomycin/ceftazidimeLevofloxacin/cefmenoximeIOL
48.63++Imipenem Sulpelin/erythromycin/
tobramycin
IOL
53.86Dermatomyositis+Vancomycin/ceftazidimeLevofloxacinImipenemIOL
60.216Axenfeld-Rieger syndrome+CeftazidimeLevofloxacin/cefmenoxime/
tobramycin/vancomycin
Imipenem/
ceftazidime
Phakia
70.77Vancomycin/ceftazidimeLevofloxacin/cefmenoximeImipenemPhakia
81.36+Vancomycin/ceftazidimeGatifloxacin/cefmenoximeIOL
93.01Diabetic mellitus+Vancomycin/ceftazidimeGatifloxacin/cefmenoxime/
vancomycin
ImipenemIOL
102.617+Vancomycin/ceftazidimeGatifloxacin/cefmenoximeFlomoxefAphakia
110.89++Vancomycin/ceftazidimeLevofloxacin/cefmenoximePhakia

SOAG = secondary open angle glaucoma, POAG = primary open angle glaucoma, PSITE = the periods from starting symptom to initiation of treatment for endophthalmitis, HPB = highly pathogenic bacteria, V = vitreous specimen, C = conjunctival specimen, A = anterior chamber’s specimen, I = specimen of removed intraocular lens, BCVA = best corrected visual acuity, IOP = intraocular pressure, BRE = bleb-related endophthalmitis, S. pneumoniae = Streptococcus pneumoniae, group A Str = group A Streptococcus, S. mitis = Streptococcus mitis, unidentifiable Str = unidentifiable Streptococcus, group G Str = group G Streptococcus, S. epidermidis = Staphylococcus epidermidis, LET = trabeculectomy, PPV = pars plana vitrectomy, and IOL = intraocular lens.