Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
Table 1
10 ocular surface symptoms’ evaluation during IPL treatments.
Symptoms
Mean ± SD
Baseline
D15
D45
D75
Dryness
9.5 ± 2.2
5.9 ± 3.5
<0.01
4.1 ± 3.1
<0.01
4.2 ± 3.0
1
Foreign body sensation
8.0 ± 4.1
4.8 ± 3.9
<0.01
3.5 ± 3.4
0.129
3.7 ± 3.2
1
Itching
3.8 ± 4.9
1.8 ± 3.4
0.03
1.1 ± 2.6
0.54
1.0 ± 2.6
1
Burning
3.8 ± 4.9
1.1 ± 2.8
<0.01
0.9 ± 2.5
1
1.3 ± 2.8
0.93
Visual fatigue
5.0 ± 5.1
3.5 ± 4.0
0.01
2.8 ± 3.4
0.24
2.5 ± 3.4
1
Blurred vision
1.0 ± 3.1
0.7 ± 2.2
0.54
0.3 ± 1.5
1
0.2 ± 0.9
1
Sensitivity to light
4.3 ± 5.0
2.3 ± 3.4
<0.01
1.8 ± 3.1
0.45
1.6 ± 2.8
1
Watering
2.5 ± 4.4
1.1 ± 2.8
0.02
0.8 ± 2.4
1
0.7 ± 1.9
1
Secretion disturbance
5.8 ± 5.0
2.8 ± 3.3
<0.01
2.7 ± 3.4
1
2.6 ± 3.8
1
Pain
4.3 ± 5.0
2.8 ± 3.9
0.04
1.5 ± 2.7
0.03
1.6 ± 3.1
1
Notes: ; compared to baseline; compared to D15; compared to D45. Statistical analysis was performed with paired -test with the Bonferroni correction. SD: standard deviation; D: day.