Propolis, a Constituent of Honey, Inhibits the Development of Sugar Cataracts and High-Glucose-Induced Reactive Oxygen Species in Rat Lenses

Figure 3

Histological images of sugar cataract formation in rats fed diets containing 15% and 25% galactose with/without propolis treatment. Rats fed a normal diet plus 0.6 g/kg/day honey showed no cataractous changes ((a) and (b)). Three weeks after feeding with 15% galactose plus 0.6 g/kg/day honey, lens fiber swelling was observed in the anterior and equatorial regions, whereas feeding with 25% galactose plus 0.6 g/kg/day honey resulted in marked swelling and liquefaction of the cortical fibers in the equatorial region of the lenses. These histological changes were suppressed by treatment with 0.6 g/kg/day propolis.