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Journal of Ophthalmology
Volume 2016, Article ID 3076031, 7 pages
Research Article

Relationship between Corneal Temperature and Intraocular Pressure in Healthy Individuals: A Clinical Thermographic Analysis

1Department of Ophthalmology, Humanitas Research Hospital, Via Alessandro Manzoni 56, Rozzano, 20089 Milan, Italy
2SBAI Department, Sapienza University of Rome, Via A. Scarpa 16, 00161 Rome, Italy
3Sooft Italia, Via Salvatore Quasimodo 136, 00144 Rome, Italy
4Faculty of Medicine and Dentistry, Sant’Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1037, 00189 Rome, Italy
5Faculty of Medicine and Dentistry, Sapienza University of Rome, Policlinic Umberto I, Viale Regina Elena 287/A, 00161 Rome, Italy

Received 1 December 2015; Revised 30 December 2015; Accepted 31 December 2015

Academic Editor: Jesús Pintor

Copyright © 2016 Claudia Fabiani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To study the geographical distribution of corneal temperature (CT) and its influence on the intraocular pressure (IOP) of healthy human volunteers. Materials and Methods. Fifteen subjects (7 M, 8 F), years old, were enrolled in this pilot, cross-sectional study. Measurements of CT were taken after one hour with closed eyelids (CET) or closed eyelids with a cooling mask (cm-CET) and compared to baseline. Results. If compared to baseline, after CET, average CT significantly increased by 0.56°C in the RE and by 0.48°C in the LE () and IOP concomitantly significantly increased by 1.13 mmHg and 1.46 mmHg, respectively, in each eye (). After cm-CET, average CT significantly decreased by 0.11°C and 0.20°C, respectively, in the RE and LE (RE ; LE ), followed by a significant IOP decrease of 2.19 mmHg and 1.54 mmHg, respectively, in each eye (RE ; LE ). Conclusion. Significant variations of CT occurred after CET and cm-CET and were directly correlated with significant differences of IOP. It can be speculated that both oxidative stress and sympathetic nerve fiber stimulation by temperature oscillations may affect the regulation of AH vortex flow and turnover, thus influencing IOP values.