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Journal of Ophthalmology
Volume 2016, Article ID 4160568, 6 pages
Research Article

Retinal Fibre Layer Thickness Measurement in Normal Paediatric Population in Sweden Using Optical Coherence Tomography

1Eye Department, Skaraborg Hospital, Skövde, Sweden
2Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden
3Karolinska Institute, Solna, Sweden
4Eye Department, Uppsala University Hospital, Uppsala, Sweden

Received 30 July 2016; Revised 11 October 2016; Accepted 25 October 2016

Academic Editor: Huazhu Fu

Copyright © 2016 Marcelo Ayala and Evangelia Ntoula. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate the correlation between peripapillary retinal nerve fibre layer (RNFL) thickness and both age and refraction error in healthy children using optical coherence tomography (OCT). Patients and Methods. 80 healthy children with a mean age of 9.1 years (range 3.8 to 16.7 years) undergoing routine ocular examination at the orthoptic section of the Ophthalmology Department were recruited for this cross-sectional study. After applying cycloplegia, the peripapillary RNFL thickness was measured in both eyes using the Topcon 3D OCT 2000 device. Results. 138 eyes were included in the analysis. The average refractive error (SE) was +1.7 D (range −5.25 to +7.25 D). The mean total RNFL thickness was 105 μm ± 10.3, the mean superior RNFL thickness was 112.7 μm ± 16.5, and the mean inferior RNFL thickness was 132.6 μm ± 18.3. We found no statistically significant effect of age on RNFL thickness (ANOVA, , ). Refraction was proven to have a statistically significant effect (ANOVA, , ) in RNFL measurements. Conclusions. Data obtained from this study may assist in establishing a normative database for a paediatric population. Refraction error should be taken into consideration due to its statistically significant correlation with RNFL thickness.