Intravitreal Melphalan for Vitreous Seeds: Initial Experience in China

Figure 1

Control of resistant seeds in case  3 (upper) and case  13 (lower). (a) and (c) Vitreous seeds (arrow) and tumor (arrow head) were still active after 4 cycles of IVC and focal consolidation in case  3 and 4 cycles of IVC and 2 cycles of OAC in case  13. (b) After 11 cycles of intravitreal melphalan, 2 additional IVC, and focal consolidation, vitreous seeds regressed into type 1 and tumor (arrow head) shrank and completely calcified. (d) After 4 cycles of intravitreal melphalan, one additional OAC, and focal consolidation, vitreous seeds regressed into type 0 and tumor (arrow head) shrank and completely calcified.

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