Combination of Intravitreal Injection of Ranibizumab and Photocoagulation for the Treatment of Aggressive Posterior Retinopathy of Prematurity with Vitreous Hemorrhage
Table 1
Characteristics of infants with AP-ROP associated with vitreous hemorrhage.
Patient number/eye
Gender
GA (weeks)
BW (g)
PCA (weeks), IVR
Zone before injection
Time after IVR (weeks), laser 1
Time after IVR (weeks), laser 2
Persistent ROP
Recurrence ROP
1
OD
M
27
1100
34
I
6
Y
OS
34
I
8
Y
2
OD
M
28
1090
35
I
2
3
Y
OS
35
Posterior II
6
Y
3
OD
M
28
1400
33
Posterior II
7
Y
4
OD
M
28
1000
36
I
2
3
Y
OS
36
I
2
Y
5
OD
F
27
1250
34
I
7
OS
34
I
7
Y
6
OD
M
28
900
36
I
2
Y
OS
36
I
2
Y
7
OD
M
28
1250
36
I
2
Y
OS
36
I
2
Y
8
OD
M
27
1125
33
I
9
OS
33
I
9
9
OD
M
31
1500
36
I
2
3
Y
10
OD
M
32
1500
38
I
2
4
Y
OS
38
I
2
4
Y
11
OD
M
32
1900
36
I
2
Y
OS
36
I
2
Y
12
OD
M
27
1130
34
I
8
Y
OS
34
I
8
Y
13
OD
M
28
1010
34
I
6
Y
OS
34
I
6
Y
14
OS
M
29
1200
35
I
1
2
Y
15
OD
F
26
950
32
Posterior II
10
Y
OS
32
Posterior II
10
Y
16
OD
M
28
1300
35
I
6
Y
OS
35
I
2
4
Y
17
OD
F
28
1100
34
I
1
2
Y
OS
34
I
4
Y
18
OD
M
27
1200
33
I
6
OS
33
I
6
Y
19
OD
F
28
1300
34
I
2
4
Y
OS
34
I
2
3
Y
20
OD
M
29
1220
34
I
8
Y
OS
34
I
8
Y
AP-ROP: aggressive posterior retinopathy of prematurity; BW: birth weight; F: female; GA: gestational age; M: male; OD: right eye; OS: left eye; PCA: postconceptual age; Y: yes.