Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis

Figure 1

Detection of TSLP, IL-4, IL-5, and IL-13 protein expression by immunohistochemistry (×400). ((a), (b), (c), (d)) No expression of TSLP, IL-4, IL-5, and IL-13 in the normal control group. ((e), (f), (g), (h)) Positive staining of TSLP, IL-4, IL-5, and IL-13 in the VKC group. ((i), (j), (k), (l)) Positive staining of TSLP, IL-4, IL-5, and IL-13 in the SAC group. ((m), (n), (o), (p)) Positive staining of TSLP, IL-4, IL-5, and IL-13 in the PAC group. Brown granules showed positive staining.

(a) No expression of TSLP in the normal control group

(b) No expression of IL-4 in the normal control group

(c) No expression of IL-5 in the normal control group

(d) No expression of IL-13 in the normal control group

(e) Positive staining of TSLP in the VKC group

(f) Positive staining of IL-4 in the VKC group

(g) Positive staining of IL-5 in the VKC group

(h) Positive staining of IL-13 in the VKC group

(i) Positive staining of TSLP in the SAC group

(j) Positive staining of IL-4 in the SAC group

(k) Positive staining of IL-5 in the SAC group

(l) Positive staining of IL-13 in the SAC group

(m) Positive staining of TSLP in the PAC group

(n) Positive staining of IL-4 in the PAC group

(o) Positive staining of IL-5 in the PAC group

(p) Positive staining of IL-13 in the PAC group