Anterior Segment Imaging in Ocular Surface Squamous Neoplasia

Figure 3

In vivo confocal microscopy findings of a patient with corneal/conjunctival intraepithelial neoplasia (CCIN). (a) demonstrates multinucleated bizarre-shaped cells in the mid-epithelial layer. In (b), a starry-sky pattern (ill-defined borders with tiny bright spots 2 to 4 μm in size within dark spaces) is seen in the basal cells. (c) demonstrates the fimbriated advancing border of CCIN at the mid-epithelial layer. There is higher reflectivity and cell density as well as pleomorphism in CCIN compared to the adjacent normal epithelium [12].

(a)

(b)

(c)