Diagnostic Performance of McMonnies Questionnaire as a Screening Survey for Dry Eye: A Multicenter Analysis

Table 4

Sensitivities, specificities, and LR+ of the McMonnies questionnaire in different gender/age groups at newly proposed cut-off points.

Gender/age	Proposed cut-off points	Sensitivity (%)	Specificity (%)	LR+
Overall	12.5	80.3	49.7	1.60
Male
Under 25 years	10.5	84.0	60.5	2.13
25–45 years	11.5	81.7	47.0	1.54
Over 45 years	12.5	80.7	40.5	1.36
Female
Under 25 years	9.5	84.2	53.6	1.81
25–45 years	13.5	80.1	46.3	1.49
Over 45 years	16.5	81.2	43.8	1.44

LR+: positive likelihood ratio.
Proposed cut-off points of each group are those with the highest specificity after setting the sensitivity at a value above 0.80.