Clinical Study

Outcomes of Infectious versus Sterile Perforated Corneal Ulcers after Therapeutic Penetrating Keratoplasty in the United States

Table 2

Comparison of baseline demographic features and preoperative characteristics of sterile and infectious perforated corneal ulcers that required therapeutic penetrating keratoplasty (with 95% confidence intervals).

Demographic features and preoperative characteristicsSterile ulcers ()Infectious ulcers () value

Age (years)57.7 (49.1–66.3)58.8 (49.2–68.4)0.8617
Range = 19 to 86Range = 18 to 91

GenderMale = 56% ()Male = 65% ()0.5394
Female = 44% ()Female = 35% ()

LateralityRight eye = 56% ()Right eye = 45% ()0.4629
Left eye = 44% ()Left eye = 55% ()

EthnicityWhite = 60% ()White = 85% ()0.1108
Hispanic = 28% ()Hispanic = 5% ()
Black = 8% ()Black = 10% ()
Asian = 4% ()Asian = 0% ()

Lens statusPhakic = 72% ()Phakic = 60% ()0.3968
Pseudophakic = 28% ()Pseudophakic = 40% ()

Contact lens wearYes = 0 (0%)Yes = 7 (35%)0.0003
No = 25 (100%)No = 13 (65%)

Previous corneal graftYes = 1 (4%)Yes = 6 (30%)0.0138
No = 24 (96%)No = 14 (70%)

Location of perforationCentral = 72% ()Central = 95% ()0.0333
Peripheral = 28% ()Peripheral = 5% ()

Preoperative best corrected visual acuity (logMAR)2.64 (2.49–2.79)2.65 (2.48–2.82)0.9311