Clinical Study
Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes
Table 1
Characteristics and surgical outcomes in fifteen patients with retinal detachment in Down syndrome.
| Case | Age | Eye | Lens | Number of retinal breaks | Type of retinal breaks | Macula | Quadrant of retinal detachment | PVR grade | Surgery | First subsequent surgery | Second subsequent surgery | Buckle details | Anatomical results | Follow-up |
| 1 | 23 | OS | Clear | 7 | HST | Off | Total | Not documented | PPV/SB/ELX/SO | ELX/Phaco + PC IOL/SO removal | | Band | Flat | 5.97 | 2 | 12 | OS | Pseudophakia | 1 | HST | Off | Total | C-anterior + posterior | PPV/SB/ELX/SO | SO removal | | Band | Flat | 5.5 | 3 | 4 | OD | Aphakia | 1 | HST | Off | Total | C-anterior | SB/CRYO | PPV/ELX/C3F8 | | Band | Flat | 39.67 | 4 | 4 | OS | Cataract | 1 | GRT | Off | Total | Not documented | PPV/SB/PPL/RR/ELX/SO | | | Band | Flat | 3.63 | 5 | 11 | OD | Cataract | 1 | GRT | Off | Total | C | PPV/SB/PPL/RR/ELX/SO | | | Band | Flat | 13.93 | 6 | 17 | OS | Cataract | 2 | HST + dialysis | Off | Total | Not documented | PPV/PPL/ELX/C3F8 | PPV/SB/ELX/SO | Secondary IOL and SO removal | n/a | Flat | 8.3 | 7 | 8 | OD | Aphakia | n/a | n/a | Off | Total | C-anterior + posterior | PPV/SB/RR/ELX/choroidal drainage/SO | | | Band and tire | Detached | 8.6 | 8 | 13 | OD | Clear | 2 | Operculated hole | Off | Three | Not documented | SB/CRYO | PPV/ELX/CRYO/C3F8 | SB removal and intravitreal AB | Band and tire | Flat | 12.37 | 9 | 6 | OS | Cataract | 1 | Operculated hole | Off | Total | C-anterior | PPV/SB/PPL/RR/ELX/C3F8 | | | Band and tire | Flat | 163.27 | 10 | 5 | OS | Pseudophakia | 1 | HST | Off | Total | C-posterior | PPV/SB/ELX/heavy SO | | | Band | Flat | 3.83 | 11 | 5 | OS | Aphakia | 3 | HST + HST + operculated hole | Off | Total | B | PPV/SB/ELX/SO | | | Band | Detached | 144 | 12 | 26 | OD | Cataract | 2 | HST | Off | Total | Not documented | SB/CRYO/ECCE | PPV/RR/ELX/C3F8 | | Band | Flat | 15.73 | 13 | 13 | OU | Cataract | 2 | Operculated hole | Off | Three | Not documented | SB/CRYO | | | Band | Flat | 3.23 | 13 | | OU | Cataract | 2 | HST | Off | Two | Not documented | SB/CRYO | | | Band and tire | Flat | 3.1 | 14 | 8 | OU | Cataract | 1 | GRT | Off | Total | Not documented | PPV/SB/PPL/ELX/SO | | | Band and tire | Flat | 210.5 | 14 | | OU | Cataract | 2 | HST | Off | Total | B | SB/lens aspiration/CRYO | | | Band | Flat | 203.97 | 15 | 14 | OU | Pseudophakia | 1 | Operculated hole | Off | Total | Not documented | PPV/SB/ELX/SO | | | | Flat | 10.53 | 15 | | OU | Pseudophakia | 1 | Operculated hole | Off | Total | Not documented | PPV/SB/ELX/C3F8 | | | | Flat | 8.6 |
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OD: right eye; OS: left eye; OU: both eyes; HST: horseshoe tear; GRT: giant retinal tear; PPV: pars plana vitrectomy; SB: scleral buckle; PPL: pars plana lensectomy; RR: relaxing retinectomy; ELX: endolaser; CRYO: cryotherapy; SO: silicon oil; C3F8: perfluoropropane; ECCE: extracapsular cataract extraction; PC IOL: posterior chamber intraocular lens; IOL: intraocular lens; AB: antibiotic; PVR: proliferative vitreoretinopathy; n/a: not available.
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