Clinical Study
Repeatability and Reproducibility of Noninvasive Keratograph 5M Measurements in Patients with Dry Eye Disease
Table 2
Intraexaminer repeatability and interexaminer reproducibility of TMH and NIKBUTs in Healthy and DED groups.
| Parameters | Healthy () | Dry eye disease () | Mean ± SD | Precision | Repeatability | CV% | ICC | 95% CI for ICC | Mean ± SD | Precision | Repeatability | CV% | ICC | 95% CI for ICC |
| Intraexaminer repeatability | | | | | | | | | | | | | TMH (mm) | 0.26 ± 0.12 | 0.10 | 0.14 | 18.89 | 0.84 | 0.75 to 0.90 | 0.24 ± 0.08 | 0.08 | 0.11 | 15.96 | 0.76 | 0.64 to 0.85 | NIKBUT first (s) | 7.25 ± 3.45 | 3.70 | 5.24 | 26.10 | 0.75 | 0.62 to 0.84 | 5.77 ± 3.04 | 2.67 | 3.76 | 23.54 | 0.82 | 0.73 to 0.89 | NIKBUT average (s) | 10.61 ± 3.93 | 3.96 | 5.60 | 19.06 | 0.78 | 0.66 to 0.86 | 8.27 ± 3.86 | 3.04 | 4.29 | 18.71 | 0.85 | 0.77 to 0.91 | Interexaminer reproducibility | | | | | | | | | | | | | TMH (mm) | 0.26 ± 0.15 | 0.10 | 0.14 | 19.76 | — | — | 0.24 ± 0.08 | 0.08 | 0.11 | 16.08 | — | — | NIKBUT first (s) | 7.35 ± 3.68 | 2.92 | 4.13 | 20.30 | — | — | 5.87 ± 3.07 | 2.51 | 3.55 | 21.85 | — | — | NIKBUT average (s) | 10.71 ± 4.11 | 3.65 | 5.15 | 17.37 | — | — | 8.21 ± 3.93 | 2.78 | 3.94 | 17.30 | — | — |
|
|
SD = standard deviation; TMH = tear meniscus height; NIKBUT = noninvasive Keratograph tear breakup time; CV = coefficient of variation; ICC = intraclass correlation coefficient; 95% CI = 95% confidence interval for the mean.
|