Relationship among Corneal Biomechanics, Anterior Segment Parameters, and Geometric Corneal Parameters

Table 6

Multivariate regression analysis of CH, CRF and age, IOP, anterior segment parameters, and keratometric values of anterior and posterior corneal surfaces.

CH

CRF

Age-gender model

Corneal keratometric; value model

Multivariate model

Age-gender model

Corneal keratometric; value model

Multivariate model

Standardized (ß)/; unstandardized (B); Coefficient (SE)

value

Standardized (ß)/; unstandardized (B); Coefficient (SE)

value

Standardized (ß)/; unstandardized (B); Coefficient (SE)

value/95% CI

Standardized (ß)/; unstandardized (B); Coefficient (SE)

value

Standardized (ß)/; unstandardized (B); value; Coefficient (SE)

value

Standardized (ß)/; unstandardized (B); Coefficient (SE)

value

Adjusted

0.455

0.432

0.416

0.545

0.544

0.537

Gender

0.086/0.297 (0.304)

0.357/−0.343–0.945

—

—

0.114/0.375 (0.316)

0.235/−0.256–1.115

0.020/0.065 (0.279)

0.836/−0.481–0.621

—

—

0.033/0.129 (0.282)

0.649/−0.426–0.678

Age

−0.275/−0.034 (0.013)

0.016/−0.044–−0.005

—

—

−0.217/−0.017 (0.008)

0.036/−0.038–−0.002

−0.124/−0.011 (0.009)

0.256/−0.031–0.007

—

—

−0.058/−0.005 (0.008)

0.546/−0.027–0.019

IOP

−0.174/−0.094 (0.049)

0.048/−0.202–−0.001

−0.142/−0.079 (0.048)

0.135/−0.168–0.027

−0.172/−0.08 (0.047)

0.061/−0.19–0.005

0.323/0.173 (0.04)

<0.001/0.093–0.262

0.346/0.181 (0.045)

<0.001/0.11–0.27

0.356/0.190 (0.041)

<0.001/0.125–0.277

ACD

0.324/1.067 (0.563)

0.055/−0.045–2.135

0.366/1.267 (0.577)

0.043/0.025–2.334

0.416/1.338 (0.551)

0.02/0.248–2.468

0.350/1.102 (0.492)

0.028/0.109–2.082

0.375/1.139 (0.49)

0.017/0.172–2.221

0.421/1.322 (0.465)

0.006/0.381–2.274

ACV

−0.129/−0.005 (0.006)

0.393/−0.017–0.007

−0.146/−0.006 (0.005)

0.464/−0.025–0.012

−0.353/−0.015 (0.007)

0.063/−0.03–0.002

−0.171/−0.006 (0.006)

0.413/−0.020–0.007

−0.119/−0.005 (0.006)

0.521/−0.019–0.009

−0.267/−0.01 (0.005)

0.126/−0.024–0.003

CV

0.035/0.017 (0.111)

0.915/−0.211–0.242

0.372/0.145 (0.1)

0.159/−0.067–0.356

0.437/0.166 (0.066)

0.009/0.042–0.332

−0.259/−0.099 (0.096)

0.298/−0.297–0.091

−0.116/−0.047 (0.09)

0.645/−0.226–0.128

0.124/0.046 (0.06)

0.474/−0.077–0.167

CCT

0.477/0.025 (0.009)

0.043/0.011–0.057

0.264/0.012 (0.11)

0.257/−0.013–0.034

0.216/0.010 (0.008)

0.278/−0.012–0.038

0.741/0.036 (0.01)

0.001/0.016–0.055

0.668/0.035 (0.008)

0.002/0.017–0.058

0.481/0.022 (0.006)

0.003/0.009–0.042

SE

−0.014/−0.008 (0.072)

0.912/−0.157–0.142

0.019/0.015 (0.078)

0.903/−0.145–0.172

−0.062/−0.038 (0.072)

0.596/−0.192–0.16

0.112/0.083 (0.062)

0.235/−0.051–0.206

0.119/0.092 (0.065)

0.183/−0.056–0.235

0.071/0.005 (0.061)

0.431/−0.077–0.177

AFKV

0.064/0.081 (0.170)

0.634/−0.256–0.417

−0.074/−0.078 (0.215)

0.743/−0.487–0.327

—

—

0.082/0.101 (0.19)

0.624/−0.278–0.477

0.032/0.035 (0.18)

0.867/−0.332–0.410

—

—

ASKV

−0.049/−0.058 (0.190)

0.759/−0.435–0.318

0.174/0.245 (0.230)

0.395/−0.265–0.675

—

—

−0.052/−0.059 (0.212)

0.814/−0.472–0.350

0.023/0.021 (0.195)

0.894/−0.374–0.399

—

—

PFKV

0.055/0.086 (0.096)

0.374/−0.105–0.276

0.132/0.194 (0.121)

0.137/−0.057–0.510

—

—

0.076/0.103 (0.101)

0.336/−0.106–0.308

0.085/0.113 (0.100)

0.267/−0.084–0.312

—

—

PSKV

−0.319/−1.971 (0.947)

0.126/−3.849–−0.093

−0.093/−0.539 (1.177)

0.648/−2.906–1.792

—

—

−0.245/−1.426 (1.071)

0.205/−3.539–0.715

−0.178/−1.001 (1.005)

0.323/−3.001–0.996

—

—

CH: corneal hysteresis; CRF: corneal resistance factor; CCT: central corneal thickness; CV: corneal volume; ACD: anterior chamber depth; ACV: anterior chamber volume; SE: spherical equivalent; IOP: intraocular pressure.