Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases

Figure 2

Mean peripapillary retinal nerve fiber layer (pRNFL) thickness of 100 multiple sclerosis (MS) patients compared with 97 healthy controls, as measured with optical coherence tomography. The peripapillary area is divided into 6 different sectors (superonasal, superotemporal, nasal, inferonasal, inferotemporal, and temporal) and average thickness. All measurements except nasal thickness were found to be significantly reduced in MS patients compared to controls (Garcia-Martin et al., data not published).