Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases

Figure 4

Example of segmentation analysis of the macular ganglion cell layer, obtained with Spectralis optical coherence tomography, in a healthy control (a) and a patient diagnosed with Parkinson disease (b). The segmentation report shows the ganglion cell layer thickness (in microns) and total volume (in mm³) of the ETDRS macular area. In this patient (b), the central and inner macular areas present thinning of the ganglion cell layer, compared with the healthy control (a).

(a)

(b)