Nonlethal Levels of Zeaxanthin Inhibit Cell Migration, Invasion, and Secretion of MMP-2 via NF-κB Pathway in Cultured Human Uveal Melanoma Cells

Figure 1

Effects of zeaxanthin on viability of uveal melanoma (UM) cells. Cultured human UM cells (C918) were seeded into 96-well plates and treated with zeaxanthin at different levels. MTT assay was used to determine the cell viability (see Material and Methods). Zeaxanthin only significantly affected the cell viability of UM cells (expressed as percentage of the controls) at 30 μM (, ). , versus control (cells cultured without zeaxanthin).