Review Article

Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease

Table 3

Vertical canalicular plugs [1825] (types of vertical canalicular plugs, manufacturers, and characteristics discussed in detail).

NameSizeMaterialTemporary/
permanent
CharacteristicsManufacturer

Form Fit1 size (diameter 0.3 mm, length 3 mm)HydrogelPermanentHydrates over 10 minutes after insertion and expands (Figure 6). With hydration it increases in size till it completely fills vertical canalicular cavity. It has low extrusion rate.Oasis

SmartPlug1 size (diameter 0.4 mm, length 6 mm) Thermosensitive acrylic materialPermanentAdjusts to shape and size of punctum. It shrinks to 1 mm after insertion to make it more comfortable by eliminating foreign body sensation. Less chance of extrusion. Can be flushed out with irrigation.Medennium

Oasis Soft Plug Extended Duration4 sizes (0.2–0.5 mm)Glycolic acid and trimethylene carbonateTemporary—extended durationEffective up to 3 months (Figure 7(a)).Oasis

DuraPlug3 sizes (0.2–0.4 mm)PCL (E-Caprolactone-L-Lactide copolymer)Temporary—extended durationLasts 2–6 months.EagleVision

Beaver-Visitec Extended Duration4 sizes (0.2–0.5 mm)Glycolic acid and trimethylene carbonateTemporary—extended durationDyed with D&C Green.
Lasts up to 3 months.
Beaver-Visitec

ProLong3 sizes (0.3–0.5 mm)Glycolic acid and trimethylene carbonateTemporary—extended durationDyed with D&C Green number 6.
Lasts up to 3 months.
FCI

Vera90 3 sizes (0.2–0.4 mm)PCL (E-Caprolactone-L-Lactide copolymer)Temporary—extended durationDyed violet with D&C Violet number 20 and is coated with calcium stearate (a noncollagenous and nonantigenic coating). Lasts up to 3 months (Figure 7(b)).Lacrivera

UltraPlug Extended Wear3 sizes (0.2–0.4 mm)PCL (E-Caprolactone-L-Lactide copolymer)Temporary—extended durationEffective for 2–6-month duration.Surgical Specialties Corporation

Oasis Soft Plug Collagen3 sizes (0.2–0.4 mm)
2 mm length.
CollagenTemporary—short durationLasts 2–5 days (see Figure 8(a)).Oasis

Eagle collagen3 sizes (0.2–0.4 mm)CollagenTemporary—short durationEffective for 3–5 days and lasts for 7–10 days.
Expands in punctum after insertion.
EagleVision

Beaver-Visitec collagen plug3 sizes (0.2–0.4 mm)CollagenTemporary—short durationLasts 7–10 days.Beaver-Visitec

FCI collagen plug3 sizes (0.2–0.4 mm)CollagenTemporary—short durationLasts 5–7 days.FCI

Vera C73 sizes (0.2–0.4 mm)CollagenTemporary—short durationEffective for 7–10 days (Figure 8(b)).Lacrivera

UltraPlug collagen3 sizes (0.2–0.4 mm)CollagenTemporary—short durationEffective for 10–14 days.Surgical Specialties Corporation