Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus

Table 1

Significant positive associations between the concentrations of the different tear mediators.

	IL-6 (pg/mL)	IL-10 (pg/mL)	CXCL8 (pg/mL)	CCL5 (pg/mL)	MMP-9 (ng/mL)	MMP-13 (ng/mL)	TIMP-1 (ng/mL)	t-PA (pg/mL)	PAI-1 (ng/mL)
IL-6 (pg/mL)			< 0.0001			< 0.0001	< 0.0001	< 0.0001
IL-10 (pg/mL)									< 0.0001
CXCL8 (pg/mL)								< 0.0001
CCL5 (pg/mL)								< 0.0001
MMP-9 (ng/mL)
MMP-13 (ng/mL)							= 0.0001		< 0.0001
TIMP-1 (ng/mL)								< 0.0001	< 0.0001
t-PA (pg/mL)									< 0.0001
PAI-1 (ng/mL)

IL: interleukin; CXCL8: chemokine (C-X-C motif) ligand 8 = IL-8; CCL5: chemokine (C-C motif) ligand 5 = RANTES: regulated on activation, normal T cell expressed and secreted; MMP: matrix metalloproteinase; TIMP-1: tissue inhibitor of metalloproteinase-1; t-PA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor (shape of relationship: linear, quadratic).