Asymmetric Outcomes of Type 1 Retinopathy of Prematurity after Bilateral Intravitreal Ranibizumab Treatment

Figure 2

Before treatment, both eyes were diagnosed as stage 3+ ROP in zone I ((a) and (b)). Nine days post-IVR, regression of ROP and plus disease was noted in both eyes, but there were vitreous and preretinal hemorrhages only in the right eye ((c) and (d)). Thirty-eight days post-IVR, hemorrhages in the right eye continued to progress even after laser treatment (e) and covered the macula; and the eye eventually required LSV treatment. One month after LSV treatment, the retina of the right eye was flat with peripheral laser spots, and there was no sign of hemorrhages. The left eye received laser treatment due to persistent zone II avascularity at 43 weeks PMA (f), which was resolved by the last follow-up (h).

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