Association of Neovascular Glaucoma with Risk of Stroke: A Population-Based Cohort Study
Table 3
Hazard ratios of ischemic stroke stratified by age and comorbidities in the univariable and multivariable Cox regression models.
Variable
Crude
Adjusted†
HR
(95% CI)
HR
(95% CI)
NVG
3.20
(2.40–4.28)
2.24
(1.51–3.33)
Age, years
1.07
(1.06–1.08)
1.06
(1.05–1.07)
Sex (female versus male)
1.08
(0.85–1.36)
—
—
Medical comorbidity
Diabetes mellitus (yes versus no)
2.41
(1.86–3.12)
1.09
(0.78–1.53)
Hypertension (yes versus no)
4.27
(3.29–5.56)
2.09
(1.55–2.82)
Hyperlipidemia (yes versus no)
1.75
(1.37–2.24)
0.92
(0.70–1.22)
Coronary artery disease (yes versus no)
2.75
(2.16–3.50)
1.17
(0.90–1.52)
Ocular comorbidity
CRVO & BRVO (yes versus no)
2.42
(1.08–5.45)
0.64
(0.27–1.51)
DMRP (yes versus no)
3.58
(2.58–4.98)
1.69
(1.05–2.72)
Retinal detachment with retinal defect (yes versus no)
1.04
(0.15–7.41)
—
—
CRAO & BRAO (yes versus no)
—
—
—
—
HTR (yes versus no)
2.78
(0.39–19.8)
—
—
Uveitis (yes versus no)
2.20
(1.17–4.14)
1.02
(0.53–1.99)
Crude HR represents the relative hazard ratio. †Variables that were found to be significant in the univariable analysis and which were included in the multivariable analysis. , .