Research Article

Association of Neovascular Glaucoma with Risk of Stroke: A Population-Based Cohort Study

Table 3

Hazard ratios of ischemic stroke stratified by age and comorbidities in the univariable and multivariable Cox regression models.

VariableCrudeAdjusted
HR(95% CI)HR(95% CI)

NVG3.20(2.40–4.28)2.24(1.51–3.33)
Age, years1.07(1.06–1.08)1.06(1.05–1.07)
Sex (female versus male)1.08(0.85–1.36)
Medical comorbidity
 Diabetes mellitus (yes versus no)2.41(1.86–3.12)1.09(0.78–1.53)
 Hypertension (yes versus no)4.27(3.29–5.56)2.09(1.55–2.82)
 Hyperlipidemia (yes versus no)1.75(1.37–2.24)0.92(0.70–1.22)
 Coronary artery disease (yes versus no)2.75(2.16–3.50)1.17(0.90–1.52)
Ocular comorbidity
 CRVO & BRVO (yes versus no)2.42(1.08–5.45)0.64(0.27–1.51)
 DMRP (yes versus no)3.58(2.58–4.98)1.69(1.05–2.72)
 Retinal detachment with retinal defect (yes versus no)1.04(0.15–7.41)
 CRAO & BRAO (yes versus no)
 HTR (yes versus no)2.78(0.39–19.8)
 Uveitis (yes versus no)2.20(1.17–4.14)1.02(0.53–1.99)

Crude HR represents the relative hazard ratio. Variables that were found to be significant in the univariable analysis and which were included in the multivariable analysis. , .