Phenotypic Description of the Spanish Multicentre Genetic Glaucoma Group Cohort

Table 1

Demographic, clinical, and treatment variables in hereditary and familiar glaucoma patients. Spain, 2015.

Group	Hereditary	Familiar	value
Number of cases	92 (61%)	60 (39%)
Age (Yrs)	66 (46;75)	59 (39;68)	0.007
Sex (female)	52 (56.5%)	31 (51.7%)	0.618
Glaucoma Subtype
POAG	72 (78.3%)	40 (66.7%)	0.335
Secondary	6 (6.5%)	4 (6.7%)
Juvenile	7 (7.6%)	8 (13.3%)
Congenital	6 (6.5%)	8 (13.3%)
Syndromic	1 (1.1%)	0 (0%)
Severity of glaucoma
OHT	4 (4.3%)	5 (8.3%)	0.319
Initial glaucoma	19 (20.7%)	22 (36.7%)	0.039
Moderate glaucoma	29 (31.5%)	12 (20%)	0.137
Severe glaucoma	40 (43.5%)	19 (31.7%)	0.174
Ophthalmic Variables
Ophthalmic comorbidities	20 (32.8%)	4 (10%)	0.09
VA (LOGMAR)	0.22 [0.05; 0.4]	0.1 [0; 0.3]	0.067
Spherical equivalent	−0.75 (−2;1)	−1.25 (−3.5; −0.25)	0.046
Optic disk lesions (Splinter Hemorrhages)	15 (16.5%)	3 (5%)	0.04
VF MD	−10.42 [−18; −4.39]	−5.475 [−13.51; −2.78]	0.046
Surgeries	63 (68.5%)	28 (46.7%)	0.01
Medical treatments
Prostaglandin analogs	45 (48.9%)	18 (30%)	0.028
Alpha adrenerics	7 (7.6%)	11 (18.3%)	0.07

YRS: years; OHT: ocular hypertension; VA: visual acuity; VF MD: visual field mean defect; median and range values are provided.