Research Article
Factors Contributing to Long-Term Severe Visual Impairment in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Table 1
Causative agents associated with SJS/TEN patients and relative frequencies.
| Inciting agents | Number of patients () | Percentage (%) |
| Medications | 83 | 93.26 | Single possible drug | 58 | 64.04 | Antibiotics | 25 | 28.09 | Penicillins | 8 | 8.99 | Sulfonamides | 8 | 8.99 | Tetracyclines | 2 | 2.25 | Quinolones | 1 | 1.12 | Macrolides | 1 | 1.12 | Other antibiotics | 5 | 5.62 | Anticonvulsants | 10 | 11.24 | Carbamazepine | 6 | 6.74 | Phenytoin | 3 | 3.37 | Phenobarbital | 1 | 1.12 | Allopurinol | 11 | 12.36 | NSAIDs | 4 | 4.49 | Antimalarials | 2 | 2.25 | Antivirals | 2 | 2.25 | Other drugs | 4 | 4.49 | Multiple possible drugs | 25 | 28.09 | Multiple antibiotics | 7 | 7.87 | Antibiotics + anticonvulsants | 5 | 5.62 | Antibiotics + NSAIDs | 2 | 2.25 | Antibiotics + antivirals | 1 | 1.12 | Antibiotics + bromhexine | 1 | 1.12 | Multiple nonantibiotics | 9 | 10.11 | Nonpharmaceutical triggers | 6 | 6.74 | Infections | 3 | 3.37 | Mycoplasma | 1 | 1.12 | Herpes simplex | 2 | 2.25 | Unidentified | 3 | 3.37 | Total | 89 | 100 |
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More than one possible drug was identified.
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