Research Article
Factors Contributing to Long-Term Severe Visual Impairment in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Table 2
Analysis of the correlation between demographics and severe visual impairment in SJS/TEN patients (
).
| | Variables | Nonsevere visual impairment (%) (, 74.16%) | Severe visual impairment (%) (, 25.84%) | OR (95% CI) | value |
| | Sex | | | | | Male
Female | 25 (37.88)
41 (62.12) | 9 (39.13)
14 (60.87) | 1.05 (0.40–2.79)
1.00 | 0.915 | | Age (years) | | | | | <40
≥40 | 28 (42.42)
38 (57.58) | 13 (56.52)
10 (43.48) | 1.76 (0.68–4.60)
1.00 | 0.245 | | Diagnosis | | | | | Overlap/TEN
SJS | 19 (28.79)
47 (77.21) | 5 (21.74)
18 (78.26) | 0.68 (0.22–2.12)
1.00 | 0.512 | | Diabetes mellitus | | | | | Yes
No | 9 (13.64)
57 (86.36) | 2 (8.70)
21 (91.30) | 0.60 (0.12–3.02)
1.00 | 0.539 | | Autoimmune diseases | | | | | Yes
No | 7 (10.61)
59 (89.39) | 3 (13.04)
20 (86.96) | 1.26 (0.30–5.36)
1.00 | 0.750 | | HIV infection | | | | | Yes
No | 13 (19.7)
53 (80.30) | 0 (0)
23 (100) | 0.16 (0.03–0.71)
1.00 | 0.021 | | Causative agents | | | | | | Nonpharmaceutical triggers | 3 (4.55) | 3 (13.04) | 7.20 (1.13–45.96) | 0.037 | | Antibiotics alone | 20 (30.30) | 12 (52.17) | 4.32 (1.44–14.02) | 0.015 | | Antibiotics with others | 7 (10.61) | 3 (13.04) | 3.09 (0.59–15.98) | 0.179 | | Nonantibiotics | 36 (54.55) | 5 (21.74) | 1.00 | |
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Statistical significance ; HIV: human immunodeficiency virus.
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