Research Article
Factors Contributing to Long-Term Severe Visual Impairment in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Table 2
Analysis of the correlation between demographics and severe visual impairment in SJS/TEN patients (
).
| Variables | Nonsevere visual impairment (%) (, 74.16%) | Severe visual impairment (%) (, 25.84%) | OR (95% CI) | value |
| Sex | | | | | Male Female | 25 (37.88) 41 (62.12) | 9 (39.13) 14 (60.87) | 1.05 (0.40–2.79) 1.00 | 0.915 | Age (years) | | | | | <40 ≥40 | 28 (42.42) 38 (57.58) | 13 (56.52) 10 (43.48) | 1.76 (0.68–4.60) 1.00 | 0.245 | Diagnosis | | | | | Overlap/TEN SJS | 19 (28.79) 47 (77.21) | 5 (21.74) 18 (78.26) | 0.68 (0.22–2.12) 1.00 | 0.512 | Diabetes mellitus | | | | | Yes No | 9 (13.64) 57 (86.36) | 2 (8.70) 21 (91.30) | 0.60 (0.12–3.02) 1.00 | 0.539 | Autoimmune diseases | | | | | Yes No | 7 (10.61) 59 (89.39) | 3 (13.04) 20 (86.96) | 1.26 (0.30–5.36) 1.00 | 0.750 | HIV infection | | | | | Yes No | 13 (19.7) 53 (80.30) | 0 (0) 23 (100) | 0.16 (0.03–0.71) 1.00 | 0.021 | Causative agents | | | | | Nonpharmaceutical triggers | 3 (4.55) | 3 (13.04) | 7.20 (1.13–45.96) | 0.037 | Antibiotics alone | 20 (30.30) | 12 (52.17) | 4.32 (1.44–14.02) | 0.015 | Antibiotics with others | 7 (10.61) | 3 (13.04) | 3.09 (0.59–15.98) | 0.179 | Nonantibiotics | 36 (54.55) | 5 (21.74) | 1.00 | |
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Statistical significance ; HIV: human immunodeficiency virus.
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