Factors Contributing to Long-Term Severe Visual Impairment in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Table 3

Analysis of the correlation between ocular findings and severe visual impairment in SJS/TEN patients with chronic ocular complications ().

Ocular findings	Nonsevere visual impairment (%); n (%),	Severe visual impairment (%); n (%),	Univariate analysis		Multivariate analysis
			OR (95% CI)	value	OR (95% CI)	value
Corneal complications
SPK
Yes; No	19 (90.48); 2 (9.52)	16 (69.57); 7 (30.43)	0.60 (0.12–3.02); 1.00	0.539
Corneal opacification
Yes; No	9 (42.86); 12 (57.14)	23 (100); 0 (0)	2.56 (1.18–5.52); 1.00	0.017
Corneal neovascularization
Yes; No	5 (23.81); 16 (76.19)	20 (86.96); 3 (13.04)	21.33 (4.42–103.06); 1.00	<0.001	15.66 (3.06–80.22)	0.001
Conjunctival complications
Hyperemia
Yes; No	7 (33.33); 14 (66.67)	13 (56.52); 10 (43.48)	2.60 (0.76–8.86); 1.00	0.127
Symblepharon
Yes; No	3 (14.29); 18 (85.71)	12 (52.17); 11 (47.83)	6.55 (1.50–28.49); 1.00	0.012	2.756 (0.48–15.92)	0.257
Eyelid complications
Trichiasis
Yes; No	7 (33.33); 14 (66.67)	9 (39.13); 14 (60.87)	1.29 (0.37–4.42); 1.00	0.690
MGD
Yes; No	8 (38.10); 13 (61.90)	6 (26.09); 17 (73.91)	1.74 (0.48–6.28); 1.00	0.395
Lens status
Cataract; No cataract	4 (19.05); 17 (80.95)	4 (17.39); 19 (82.61)	0.89 (0.58–2.15); 1.00	0.887

Statistical significance . Statistical significance ; MGD: meibomian gland dysfunction; SPK: superficial punctate keratopathy.