Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study

Table 4

Associations of iris conicity and anthropometric and ocular characteristics including ocular geometric parameters in the Gutenberg Health Study separated for refractive error (myopic eyes (sphere < −0.5 D), emmetropic eyes (sphere: ), hyperopic eyes (sphere > 0.5 D), and eyes with astigmatism >−1.0D. CI: confidence interval.

(a) Analysis of myopic subjects ( eyes)

Iris conicity (°) ~	Beta estimate	Lower 95% CI	Upper 95% CI	value
Sex	−0.45	−0.88	−0.02	0.04
Age (y)	−0.08	−0.10	−0.06	<0.0001
Height (m)	1.75	−0.63	4.14	0.15
Weight (kg)	0.00	−0.01	0.01	0.53
Smoking	0.23	−0.21	0.67	0.31
IOP (mmHg)	−0.02	−0.08	0.04	0.48
Corneal power (dpt)	0.04	−0.07	0.15	0.46
Anterior chamber depth (mm)	−0.77	−1.36	−0.17	0.01
CCT (μm)	−0.00	−0.01	0.00	0.40
Lens thickness (mm)	2.57	2.00	3.14	<0.0001
Axial length (mm)	−0.04	−0.20	0.13	0.67
Mean pupil diameter (mm)	−0.22	−0.59	0.15	0.25

(b) Analysis of emmetropic subjects ( eyes)

Iris conicity (°) ~	Beta estimate	Lower 95% CI	Upper 95% CI	value
Sex	−0.15	−0.60	0.30	0.52
Age (y)	−0.06	−0.08	−0.04	<0.0001
Height (m)	1.77	−0.86	4.40	0.19
Weight (kg)	0.01	−0.01	0.02	0.30
Smoking	−0.31	−0.69	0.06	0.10
IOP (mmHg)	−0.02	−0.08	0.04	0.54
Corneal power (dpt)	−0.09	−0.25	0.08	0.31
Anterior chamber depth (mm)	−0.31	−0.97	0.36	0.37
CCT (μm)	0.00	−0.00	0.01	0.59
Lens thickness (mm)	3.02	2.37	3.66	<0.0001
Axial length (mm)	−0.56	−0.95	−0.16	0.006
Mean pupil diameter (mm)	−0.08	−0.46	0.30	0.69

(c) Analysis of hyperopic subjects ( eyes)

Iris conicity (°) ~	Beta estimate	Lower 95% CI	Upper 95% CI	value
Sex	−0.51	−0.90	−0.11	0.01
Age (y)	−0.06	−0.07	−0.04	<0.0001
Height (m)	0.10	−2.17	2.36	0.93
Weight (kg)	−0.00	−0.01	0.01	0.80
Smoking	0.28	−0.11	0.67	0.15
IOP (mmHg)	−0.06	−0.11	−0.01	0.02
Corneal power (dpt)	−0.05	−0.17	0.08	0.49
Anterior chamber depth (mm)	−0.37	−0.96	0.23	0.23
CCT (μm)	−0.00	−0.01	0.00	0.47
Lens thickness (mm)	2.70	2.18	3.22	<0.0001
Axial length (mm)	−0.55	−0.80	−0.30	<0.0001
Mean pupil diameter (mm)	−0.09	−0.43	0.25	0.59

(d) Analysis of subjects with high astigmatism ( eyes)

Iris conicity (°) ~	Beta estimate	Lower 95% CI	Upper 95% CI	value
Sex	0.13	−0.61	0.85	0.74
Age (y)	−0.10	−0.13	−0.07	<0.0001
Height (m)	1.76	−2.31	5.84	0.40
Weight (kg)	0.00	−0.01	0.02	0.90
Smoking	0.18	−0.48	0.83	0.60
IOP (mmHg)	0.04	−0.05	0.13	0.42
Corneal power (dpt)	0.09	−0.06	0.23	0.25
Anterior chamber depth (mm)	−0.89	−1.80	0.02	0.056
CCT (μm)	−0.01	−0.02	−0.00	0.03
Lens thickness (mm)	2.97	2.01	3.94	<0.0001
Axial length (mm)	0.08	−0.13	0.30	0.45
Mean pupil diameter (mm)	−0.07	−0.65	0.51	0.81