Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases

Figure 5

Schematic images of the cultured corneal endothelial cell (CEC) injection therapy. (a) Coinjection of cultured CECs with a ROCK inhibitor into the anterior chamber; (b) patient in the facedown position, to allow the CECs to sink down to the anterior chamber side of the cornea; (c) maintenance of the facedown position for 3 hours; (d) regeneration of the corneal endothelium by the injected cultured CECs. Reproduced from Okumura et al. [48].

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