Predictive Factors of the Standard Cross-linking Outcomes in Adult Keratoconus: One-Year Follow-Up
Table 4
Univariate linear regression of the baseline predictive factors and its significance on the treatment outcomes.
Baseline predictive factors
Changes in BCVA
Changes in K max
Standardized B coefficient
Significant value
95% CI
Standardized B coefficient
Significant value
95% CI
Age
0.0023
0.142
0.0025–0.125
−0.0142
0.695
−0.008–0.005
Gender (male predominance)
0.0115
0.621
0.752–1.874
0.0291
0.452
−0.582–1.285
Positive family history
0.008
0.854
−0.145–0.174
0.0983
0.345
0.184–1.114
UCVA (logMAR)
−0.917
0.140
0.350–0.449
0.931
0.162
1.450–2.374
BCVA (logMAR)
−0.945
<0.001
0.505–0.615
−0.889
<0.001
1.262–2.223
K max (D)
−0.816
0.001
0.005–0.007
−1.000
0.081
0.981–0.991
Thinnest pachymetry (μm)
0.792
0.001
0.000–0.001
0.993
0.132
0.098–0.104
Eccentricity of the cone (mm)
0.794
0.101
0.152–0.236
0.946
<0.001
1.716–2.149
BCVA: best-corrected visual acuity; UCVA: uncorrected visual acuity; logMAR: logarithm of minimal angle of resolution; K max: maximum keratometry; D: diopter; CI; confidence interval; B coefficient: the value which indicates how the dependent variable will vary per unit change in the predictive variable; test used: univariate linear regression test; Significant at the value <0.05.
