<i>PRPF3</i>-Associated Autosomal Dominant Retinitis Pigmentosa and <i>CYP4V2</i>-Associated Bietti’s Crystalline Corneoretinal Dystrophy Coexist in a Multigenerational Chinese Family

<div>The depth and coverage of next-generation sequencing of the <i>PRPF3</i> gene and the chromatogram obtained by Sanger sequencing (patient III:9). (a) The rectangle shows the averaged sequencing depth and coverage of the family for all 16 exons of the <i>PRPF3</i> gene as screened by next-generation sequencing. (b) Sanger sequencing detected a heterozygous mutation (c.1481C&gt;T, p.Thr494Met) in <i>PRPF3</i>.</div>

Journal of Ophthalmology

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Figure 2

Figure 2: <i>PRPF3</i>-Associated Autosomal Dominant Retinitis Pigmentosa and <i>CYP4V2</i>-Associated Bietti’s Crystalline Corneoretinal Dystrophy Coexist in a Multigenerational Chinese Family 

Figure 2 | PRPF3-Associated Autosomal Dominant Retinitis Pigmentosa and CYP4V2-Associated Bietti’s Crystalline Corneoretinal Dystrophy Coexist in a Multigenerational Chinese Family 