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Number of CNV-ME, mean ± SD | 37.5 ± 6.8 |
12 months | 9.3 ± 2.0 |
24 months | 8.0 ± 2.0 |
36 months | 7.2 ± 2.1 |
48 months | 6.9 ± 1.9 |
60 months | 6.1 ± 2.2 |
Missed CNV-ME, mean ± SD | 1.6 ± 1.7 |
Due to disease, n (%) | 111 (59.0) |
Due to unknown reasons, n (%) | 77 (41.0) |
Patients with at least 1, n (%) | 78 (66.7) |
Patients with more than 1, n (%) | 49 (41.9) |
Number of injections, mean ± SD | 21.7 ± 12.4 |
12 months | 6.0 (2.4) |
24 months | 4.2 (3.1) |
36 months | 3.7 (3.1) |
48 months | 4.0 (3.7) |
60 months | 3.8 (3.7) |
Missed injections, n | 27 |
Patients with at least 1, n (%) | 25 (21.4) |
Patients with more than 1, n (%) | 2 (1.7) |
Treatment suspensions, mean ± SD | 5.3 ± 3.0 |
Due to medical indication, n (%) | 562 (90.8) |
Without medical indication, n (%) | 57 (9.2) |
Treatment reinitiations, mean ± SD | 4.7 ± 3.1 |
Patients needing further treatment at the end of follow-up, n (%) | 51 (43.6) |
Development of atrophy, n (%) | 83 (70.9) |
During treatment, n (%) | 52 (62.7) |
During suspension with medical indication, n (%) | 31 (37.3) |
Development of RPE tear, n (%) | 9 (7.7) |
During treatment, n (%) | 8 (88.9) |
During suspension with medical indication, n (%) | 1 (11.1) |
Development of subretinal fibrosis, n (%) | 75 (68.5) |
During treatment, n (%) | 61 (81.3) |
During suspension with medical indication, n (%) | 14 (18.7) |
Sudden massive hemorrhages | |
Episodes during treatment, n (%) | 24 (51.1) |
Episodes during suspension with medical indication, n (%) | 23 (48.9) |
Patients with at least 1 episode, n (%) | 38 (32.5) |
Patients with more than 1 episode, n (%) | 9 (7.7) |
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