Research Article
The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course
Table 1
Characteristics of patients with GD.
| | Characteristics | Median (25–75 percentiles) | | All sample
() | GO−
() | GO+
() |
| | Age at diagnosis, year | 13.3 ± 2.3 | 12.7 ± 2.9 | 13.9 ± 3.4 | 0.09 | Active smoking, n (%)
Passive smoking, n (%) | 9 (13.4)
14 (20.1) | 6 (12.2)
9 (18.4) | 3 (16.7)
5 (27.8) | 0.6
0.4 | | Proptosis, mm | 16.6 ± 1.2 | 15.7 ± 1.3 | 17.4 ± 1.7 | <0.001 | | Palpebral fissure, mm | 11.9 ± 0.9 | 11.3 ± 0.6 | 12.9 ± 1.3 | <0.001 | | CAS | 0.45 ± 0.8 | 0.08 ± 0.27 | 1.44 ± 1.28 | <0.001 | | Duration of the first treatment, months (range) | 19 (12–34) | 16 (12–28.5) | 29 (17.5–34) | <0.001 | | Duration of the first remission, months (range) | 10.2 (2–22.5) | 13 (5–22.5) | 5 (2–11.5) | <0.001 | | There was noted only one attack of GD, n (%) | 31.8 (28) | 55.1 (27) | 11.1 (2) | 0.001 | | Relapse within 1 year after remission, n (%) | 41.8 (28) | 38.8 (19) | 50.0 (9) | 0.4 | | Relapse within 2 years after remission, n (%) | 38.8 (26) | 36.7 (18) | 56.6 (10) | 0.2 | | Duration of the first remission more than 1 year, n (%) | 58.2 (39) | 61.2 (30) | 33.3 (6) | 0.02 | | GD recurrence within 2 years post therapy, n (%) | 16.4 (11) | 14.3 (7) | 27.8 (5) | 0.2 |
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