Suppression of Retinal Neovascularization by Inhibition of Galectin-1 in a Murine Model of Oxygen-Induced Retinopathy

Figure 9

Quantification of Gal-1 and Nrp-1 staining at P17. (a) and (b) Whole-mount staining of Gal-1 and IB4 in the OIR-OTX008 group and the OIR-PBS group. (c) Quantification of Gal-1 staining showed that OTX008 injection significantly reduced the Gal-1+ area than in the OIR-PBS control group (). (d) and (e) Whole-mount staining of Nrp-1 and IB4 in the OIR-OTX008 group and the OIR-PBS group. (f) Quantification of Nrp-1 staining indicated that OTX008 injection significantly reduced the Nrp-1+ area than in the OIR-PBS control group (). Magnification 100x, scale , data were presented as the mean ± SD, per group.

(a)

(b)

(c)

(d)

(e)

(f)