Familial Retinoblastoma: Raised Awareness Improves Early Diagnosis and Outcome

Table 2

Clinical features and outcome of eye with retinoblastoma in both proband and nonproband groups.

		Proband		Nonproband		value
Presenting symptom	Leukocoria	15	83%	10	38%	0.1
	Squint	2	11%	6	23%
	Screening	0	0%	10	38%
IIRC group at diagnosis	A	0	0%	12	27%	0.0001
	B	1	3%	14	30%
	C	4	13%	7	16%
	D	20	65%	8	17%
	E	6	19%	4	9%
Eye salvage rate	Yes	14	45%	36	80%
	No	17	55%	9	20%
BCVA	Less than 0.5	6	18%	5	20%
	Better than 0.5	8	26%	13	50%

IIRC: International Intraocular Retinoblastoma Classification; BCVA: best-corrected visual acuity at the last date of follow-up per eye.
Eye salvage rate per eye.