The Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Anterior Segment

Figure 4

Immunohistochemistry of collagen type I in the cornea at different time points. ((A), (B)) 1 day and 7 days after operation, there was no expression of collagen type I in the focal zone. The expression of collagen type I out of the focal zone was normal (indicated by an arrow), 400x; (C) 15 days after the operation, the expression of collagen type I increased in the focal zone (indicated by an arrow), 400x; ((D), (E), and (F)) 30 days, 60 days, and 90 days after the operation, the expression of collagen type I was observed in the corneal epithelium, stroma, and endothelium (indicated by an arrow), 400x; (G) in the control group, collagen type I was expressed in the corneal epithelium, stroma, and endothelium, 400x. Scale bar = 100 μm.