Review Article
Clinical Features and Treatments of Syphilitic Uveitis: A Systematic Review and Meta-Analysis
Table 2
Clinical characteristics of patients with syphilitic uveitis.
| | Study | Bilaterality (%) | AU (%) | IU (%) | PU (%) | PAU (%) | ASPPC (%) | Retinitis, retinal
vasculitis, neuroretinitis | Papillitis,
optic neuritis | HIV-positive (%) | CSF VDRL
positive (%) |
| | Bollemeijier (2016) | 63.5 | 15.8 | 1.4 | 30.2 | 47.5 | — | 86.0 | 74.0 | 35.9 | 38.7 | | Dai (2016) | 20.0 | — | — | — | — | — | 22.0 | 14.6 | 0.0 | 36.0 | | Fonollosa (2016) | 86.0 | 14.0 | 0.0 | 52.0 | 34.0 | 8.6 | 23.7 | 33.3 | 34.0 | 15.0 | | Sahin (2016) | 41.7 | 29.4 | 11.8 | 29.4 | 11.8 | — | — | 5.9 | 0.0 | — | | Tsuboi (2016) | 50.0 | 10.0 | 6.7 | 50.0 | 20.0 | 6.7 | — | 53.3 | 100.0 | — | | Zhang (2016) | 73.3 | — | — | — | — | 3.0 | 17.0 | 9.0 | 13.3 | — | | Lee (2015) | 81.3 | 13.8 | — | 27.6 | 44.8 | — | — | 13.8 | 62.5 | 20.0 | | Moradi (2015) | 74.3 | 36.1 | 23.0 | 8.2 | 45.9 | 3.3 | — | — | 54.3 | 47.1 | | Northey (2015) | 52.0 | 32.4 | — | 67.6 | 2.7 | 2.7 | 27.0 | 27.0 | 32.0 | 42.9 | | Shen (2015) | 61.5 | 4.8 | — | — | 9.5 | — | 52.4 | 14.3 | 7.7 | — | | Mathew (2014) | 56.0 | 9.5 | 1.6 | 12.7 | 41.3 | — | — | 22.2 | 31.7 | — | | Rodrigues (2014) | 58.3 | 5.3 | — | 21.1 | 57.9 | — | 5.3 | 10.5 | 66.7 | 22.2 | | Yap (2014) | 50.0 | 33.3 | 5.6 | 27.8 | 33.3 | — | 44.4 | 33.3 | 25.0 | 44.4 | | Restivo (2013) | 50.0 | — | 9.5 | 28.6 | 50.0 | — | — | — | 42.9 | 42.9 | | Eandi (2012) | | | | | | | | | | | | Yang (2012) | 84.2 | — | — | 85.7 | — | 5.7 | 94.3 | 28.6 | 21.0 | — | | Balaskas (2011) | 61.5 | 0.0 | — | 50.0 | 45.2 | — | 69.0 | 31.0 | 7.7 | 5.5 | | Hughes (2010) | 46.2 | 10.5 | 10.5 | 36.8 | 47.4 | — | 73.7 | — | 46.1 | 60.0 | | Li (2010) | 69.2 | 22.7 | — | 23.1 | 30.8 | — | — | 27.3 | 100.0 | 50.0 | | Kunkel (2009) | 71.0 | 17.1 | — | 41.7 | 9.8 | — | — | 26.8 | 45.8 | 29.1 | | Fonollosa (2009) | 50.0 | — | — | 5.6 | 94.4 | — | 27.8 | 27.8 | 75.0 | 75.0 | | Anshu (2008) | 31.8 | 75.9 | 10.3 | 13.8 | 27.6 | 3.4 | 27.6 | 27.6 | 0.0 | 50.0 | | Hong (2007) | 75.0 | — | — | 7.1 | 78.6 | — | 14.3 | 28.6 | 0.0 | 20.0 | | Parc (2007) | 10.0 | — | — | 100.0 | — | — | 36.4 | 72.7 | 80.0 | 22.2 | | Tran (2005) | 67.0 | 10.0 | — | — | 20.0 | 30.0 | 35.0 | 25.0 | 100.0 | — | | Shalaby (1997) | 83.0 | 30.8 | 23.1 | — | 38.5 | — | — | 7.7 | 100.0 | 63.6 | | Li (2011) | 85.0 | — | — | 41.7 | 58.3 | — | 66.7 | 41.7 | 83.0 | 25.0 | | Ormerod (2001) | 90.4 | — | — | — | 5.0 | 2.0 | 17.5 | 2.5 | 33.3 | 47.4 | | Browning (2000) | 71.4 | — | — | — | — | — | 54.2 | 12.5 | 36.0 | 22.2 | | Villanueva (2000) | — | — | — | — | 15.0 | — | 10.0 | — | 33.3 | 20.0 | | Deschenes (1992) | 71.4 | 85.7 | — | >0 | >0 | — | 28.6 | 14.3 | 66.7 | — | | Tamesis (1990) | 44.4 | 29.4 | 5.9 | 17.6 | 47.1 | — | 11.8 | 17.6 | 8.0 | 50.0 |
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ASPPC: acute syphilitic posterior placoid choroiditis; AU: anterior uveitis; CSF: cerebrospinal fluid; HIV: human immunodeficiency virus; IU: intermediate uveitis; PAU: panuveitis; PU: posterior uveitis; VDRL: venereal disease research laboratory test.
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