Review Article

Clinical Features and Treatments of Syphilitic Uveitis: A Systematic Review and Meta-Analysis

Table 3

Clinical phenotypes of syphilitic uveitis.

PhenotypeNumber of studies (%)

Papillitis, optic neuritis, or neuroretinitis28 (87.5)
Panuveitis24 (75.0)
Retinitis, retinal vasculitis23 (71.9)
Anterior uveitis21 (65.6)
Posterior uveitis20 (62.5)
 ASPPC10 (31.3)
 Choroiditis or chorioretinitis8 (25.0)
Intermediate uveitis11 (34.4)
Macular edema7 (21.9)
IOP increased6 (18.8)
Serous retinal detachment6 (18.8)
Necrotizing retinitis5 (15.6)

ASPPC: acute syphilitic posterior placoid choroiditis; IOP: intraocular pressure; number of studies that included patients with the specified clinical phenotype (of 32 studies included in this review).