Review Article

Clinical Features and Treatments of Syphilitic Uveitis: A Systematic Review and Meta-Analysis

Table 5

Ocular complications and systemic adverse events (318 eyes).

ComplicationsNumber of events
(proportion, %)
N/N (%)

Ocular complications
 Cataract41 (29.5)12.9
 Ocular HTN15 (10.8)4.7
 PS15 (10.8)4.7
 Chorioretinal scarring12 (8.6)3.8
 ERM12 (8.6)3.8
 ME10 (7.2)3.1
 Optic disc atrophy10 (7.2)3.1
 RD8 (5.8)2.5
 PVR5 (3.6)1.6
 Phthisis bulbi4 (2.9)1.3
 Others7 (5.0)2.2
 Total139 (100)43.7
Systemic adverse events
 Jarisch-Herxheimer reaction32.2 (of 136
patients)

ERM: epiretinal membrane; HTN: hypertension; ME: macular edema; PS: posterior synechiae; PVR: proliferative vitreoretinopathy; RD: retinal detachment; percentage of eyes with ocular complications in a total of 318 eyes included in eight studies that reported complications.