Review Article
Clinical Features and Treatments of Syphilitic Uveitis: A Systematic Review and Meta-Analysis
Table 6
Subgroup analysis of efficacy of antibacterial monotherapy of syphilitic uveitis.
| | Subgroup | Number of studies | Pooled success rate (95% CI) | I2 (%) | Pheterogeneity |
| | Publication year | | | | | | >2009 | 6 | 0.86 (0.71–0.97) | 82.4 | <0.0001 | | ≤2009 | 9 | 0.94 (0.85–1.00) | 70.6 | 0.0007 | | Number of eyes | | | | | | <25 | 9 | 0.93 (0.85–0.99) | 57.9 | 0.0149 | | ≥25 | 6 | 0.88 (0.72–0.98) | 87.7 | <0.0001 | | Geographical location | | | | | | North America | 7 | 0.88 (0.74–0.98) | 81.5 | <0.0001 | | Europe | 6 | 0.92 (0.79–0.99) | 75.7 | 0.0010 | | China | 2 | 0.98 (0.85–1.00) | 48.2 | 0.1648 | | HIV positivity (%) | | | | | | ≥50 | 7 | 0.93 (0.78–1.00) | 81.3 | <0.0001 | | <50 | 8 | 0.90 (0.80–0.97) | 74.6 | 0.0003 | | Follow-up duration (months) | | | | | | ≥12 | 4 | 0.90 (0.79–0.98) | 64.9 | 0.0151 | | <12 | 7 | 0.97 (0.91–1.00) | 55.8 | 0.0348 | | Unclear | 4 | 0.76 (0.50–0.95) | 78.9 | 0.0026 |
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CI: confidence interval; HIV: human immunodeficiency virus.
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