Journal of Ophthalmology / 2017 / Article / Tab 6

Review Article

Clinical Features and Treatments of Syphilitic Uveitis: A Systematic Review and Meta-Analysis

Table 6

Subgroup analysis of efficacy of antibacterial monotherapy of syphilitic uveitis.

SubgroupNumber of studiesPooled success rate (95% CI)I2 (%)Pheterogeneity

Publication year
 >200960.86 (0.71–0.97)82.4<0.0001
 ≤200990.94 (0.85–1.00)70.60.0007
Number of eyes
 <2590.93 (0.85–0.99)57.90.0149
 ≥2560.88 (0.72–0.98)87.7<0.0001
Geographical location
 North America70.88 (0.74–0.98)81.5<0.0001
 Europe60.92 (0.79–0.99)75.70.0010
 China20.98 (0.85–1.00)48.20.1648
HIV positivity (%)
 ≥5070.93 (0.78–1.00)81.3<0.0001
 <5080.90 (0.80–0.97)74.60.0003
Follow-up duration (months)
 ≥1240.90 (0.79–0.98)64.90.0151
 <1270.97 (0.91–1.00)55.80.0348
 Unclear40.76 (0.50–0.95)78.90.0026

CI: confidence interval; HIV: human immunodeficiency virus.

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