Journal of Ophthalmology / 2017 / Article / Tab 1

Research Article

Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys

Table 1

Additive effect by ripasudil for categories of glaucoma therapeutic agents.

CategoriesTargetAdditive effect with ripasudil

β-BlockersSuppression of aqueous humor productionIOP reduction
Prolonged duration
CAIIOP reduction
Prolonged duration
Combination of β-blockers and CAIIOP reduction
Prolonged duration

PG analogsPromotion of uveoscleral outflowIOP reduction
Prolonged duration

α2-AgonistsSuppression of aqueous humor production and promotion of uveoscleral outflowIOP reduction
Prolonged duration
αβ-BlockersProlonged duration
Combination of PG analogs and β-blockersIOP reduction
Prolonged duration

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