Neovascular Age-Related Macular Degeneration in the Very Old (≥90 Years): Epidemiology, Adherence to Treatment, and Comparison of Efficacy

Figure 1

Treatment adherence in relation to different reasons for discontinuation shown in time-to-event curves. Comparing Aflibercept (red) with Ranibizumab (blue) did not show any statistically significant differences. (a) Death was an issue throughout the entire follow-up period. (b) Patients feeling burdened by the treatment opted out mostly within the first year. (c) Treatment discontinuation due to inactive CNV/dry macula was only seen after the first year. (d) Treatment discontinuation due to a fibrotic/untreatable lesion was mostly within the first year.