Research Article

Neovascular Age-Related Macular Degeneration in the Very Old (≥90 Years): Epidemiology, Adherence to Treatment, and Comparison of Efficacy

Table 1

Reasons for discontinuation of anti-VEGF treatment using either Aflibercept or Ranibizumab among patients with neovascular age-related macular degeneration aged ≥90 years.

Aflibercept ()Ranibizumab () value

Death during follow-up, n (%)7 (13)9 (15)0.809
Burdened by treatment/opted out of treatment, n (%)6 (11)10 (16)0.434
Inactive CNV, dry macula, and referral of patient to the primary sector, n (%)5 (9)3 (5)0.470
Treatment stopped due to development of a fibrotic/untreatable lesion, n (%)6 (11)11 (18)0.314

values were calculated using the χ2-test for all categories, but inactive CNV, dry macula, and referral of patient to the primary sector was calculated using Fisher’s exact test due to groups with <5.