Research Article

Neovascular Age-Related Macular Degeneration in the Very Old (≥90 Years): Epidemiology, Adherence to Treatment, and Comparison of Efficacy

Table 4

Two-year results on Ranibizumab treatment for neovascular age-related macular degeneration in patients aged ≥90 years.

Ranibizumab ()
Mean (95% CI)P value

ΔBCVA, ETDRS letters
 4 months1.2 (−3.0 to 5.3)0.570
 12 months−0.5 (−4.8 to 3.7)0.800
 24 months−5.8 (−10.9 to −0.6)0.028
Δ average CRT, μm
 4 months−114 (−155 to −73)<0.001
 12 months−95 (−138 to −52)<0.001
 24 months−98 (−143 to −52)<0.001

BCVA: best-corrected visual acuity; CRT: central retinal thickness; CI: confidence interval. values were calculated using the one sample t-test with test value = 0.