The Protective Effects of αB-Crystallin on Ischemia-Reperfusion Injury in the Rat Retina

Figure 1

Representative photographs of the rat retina after I/R injury. In the 3 groups (), (a), (b), and (c) are for 24 h; (d), (e), and (f) are for 1 w; and (g), (h), and (i) are for 1 m post I/R. In sham group, the GCL and INL were obvious and well organized. The IPL and INL in I/R + vehicle group was obviously thinner, and the number of RGCs significantly declined, while in I/R + αB-crystallin group, the retina was more normal in structure, with a thicker INL than in I/R + vehicle group. GCL: ganglion cell layer; INL: inner nuclear layer; IPL: inner plexiform layer; ONL: outer nuclear layer. Scale bar = 25 μm.