The Protective Effects of αB-Crystallin on Ischemia-Reperfusion Injury in the Rat Retina

Table 1

Thickness of the retinal layers and GCL cell count at 24 h, 1 w, and 1 m after I/R ().

Group	Thickness (μm)				GCL cell number
Each	Overall	IPL	INL	ONL	(200 μm)
Sham	158.84 ± 3.75	52.86 ± 2.72	29.66 ± 1.99	49.80 ± 1.42	27.00 ± 1.10
24 h I/R + vehicle	121.10 ± 3.03^a,	35.62 ± 2.92^a,	21.38 ± 1.13^a,	40.56 ± 0.98^a,	7.67 ± 1.51^a,
24 h I/R + αB	144.05 ± 2.55^b,	45.07 ± 1.68^b,	24.46 ± 1.61^b,	48.56 ± 2.66^b,	15.67 ± 1.97^b,
1 w I/R + vehicle	120.32 ± 2.14^a,	36.06 ± 1.41^a,	22.33 ± 0.93^a,	35.89 ± 2.15^a,	9.33 ± 2.42^a,
1 w I/R + αB	134.03 ± 1.10^b,	43.98 ± 0.49^b,	27.68 ± 0.72^b,	42.42 ± 1.41^b,	15.00 ± 2.10^b,
1 m I/R + vehicle	82.83 ± 4.14^a,	24.67 ± 1.72^a,	16.77 ± 1.12^a,	28.23 ± 3.53^a,	9.67 ± 1.51^a,
1 m I/R + αB	133.49 ± 1.69^b,	42.31 ± 1.41^b,	27.91 ± 0.67^b,	40.26 ± 2.71^b,	17.33 ± 1.63^b,

^aCompared with sham group. ^bCompared with I/R + vehicle; . INL: inner nuclear layer; IPL: inner plexiform layer; ORL: outer retinal layer; GCL: ganglion cell layer; I/R: ischemia-reperfusion.