Effect of Preoperative Intravitreal Bevacizumab on the Surgical Outcome of Neovascular Glaucoma at Different Stages

Table 4

Result of cox proportional hazard analysis for assessing risk factors of surgical failure (total of 70 eyes).

Variables	Univariate		Multivariate
	HR (95% CI)	value	HR (95% CI)	value
Preoperative PRP (versus not done)	0.38 (0.14–1.02)	0.056	0.40 (0.15–1.09)	0.072
Presence of NVA (versus absence)	0.91 (0.20–4.20)	0.907
PAS more than 50% (versus less than 50%)	2.33 (0.96–5.62)	0.061	2.25 (0.92–5.47)	0.075
IVB group (versus control)	0.47 (0.20–1.11)	0.085
Number of IVB injection (per 1-time injection)	0.60 (0.35–1.03)	0.062
Baseline IOP (per 1 mmHg)	1.03 (0.99–1.08)	0.144
Baseline BCVA (per 1 LogMAR)	1.23 (0.78–1.93)	0.368

HR = hazard ratio; CI = confidence interval; PRP = panretinal photocoagulation; NVA = neovascularization of angle; PAS = peripheral anterior synechiae; IVB = intravitreal bevacizumab; IOP = intraocular pressure; BCVA = best-corrected visual acuity; MAR = minimal angle of resolution. Variables with in univariate analysis (PRP, PAS extent, IVB, and number of IVB injection) were entered into multivariate analysis. Multivariate model using a backward elimination approach based on likelihood ratio; variables were entered in the model if and removed if in the saturated multivariate model.