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Journal of Ophthalmology
Volume 2017, Article ID 7947854, 6 pages
Research Article

Long-Term Outcomes of Primary Trabeculectomy in Diabetic Patients without Retinopathy with Primary Angle-Closure Glaucoma

Department of Ophthalmology, The Second People’s Hospital of Jinan, No. 148 Jingyi Road, Jinan 250001, China

Correspondence should be addressed to Miaomiao Zhang; moc.621@333_mmz

Received 11 September 2016; Accepted 23 January 2017; Published 26 February 2017

Academic Editor: Rachel W. Kuchtey

Copyright © 2017 Jian Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate primary trabeculectomy with adjunctive mitomycin-C (MMC) in diabetic patients without retinopathy with primary angle-closure glaucoma (PACG). Design. This is a retrospective case series comparison. Participants. This retrospective trial compared outcomes of 88 eyes that underwent trabeculectomy in patients with diabetes mellitus (DM) without retinopathy and in 97 patients without DM. Methods. In this study, the intraocular pressure (IOP), visual acuity, visual field, and postoperative complications were compared between the two groups. Qualified surgical success is defined as an IOP between 6 and 18 mmHg with or without topical antiglaucoma medication. Results. After a follow-up of 5 years, the IOP decreased from a mean basal IOP of  mmHg to  mmHg in the DM group and from  mmHg to  mmHg in the control group. The mean number of antiglaucoma medications was and preoperatively () whereas it was and at the 5-year follow-up (). The 5-year qualified surgical success rates were 42.9% and 65.4% for both groups (; log-rank test). Encysted blebs were seen in 21 (23.9%) patients in the DM group and in 12 (12.4%) patients in the control group (). Conclusion. PACG patients with DM without retinopathy undergoing primary trabeculectomy with MMC may have a lower long-term surgical survival rate compared with patients without DM.