Glaucomatous Optic Nerve Changes and Thyroid Dysfunction in an Urban South Korean Population
Table 6
Adjusted odds ratio and 95% confidence intervals of glaucoma stratified by thyroid function.
Variables
Odds ratio
95% confidence interval
value
Age
1.029
(1.024–1.035)
<0.001
Sex (male)
1.783
(1.583–2.007)
<0.001
Diabetes
1.087
(0.878–1.345)
0.445
Hypertension
1.860
(1.632–21,192)
<0.001
Hyperlipidaemia
0.963
(0.850–1.090)
0.547
Current smoker
0.878
(0.781–0.988)
0.031
T3 (pg/mL)
(All subjects)
1st quartile (<2.87)
1 (reference)
2nd quartile (2.87–3.12)
1.008
(0.873–1.164)
0.915
3rd quartile (3.12–3.40)
1.134
(0.984–1.306)
0.082
4th quartile (≥3.40)
1.036
(0.892–1.203)
0.646
T3 (pg/mL)
(20 ~ 39 age subjects)
1st quartile (<2.87)
1 (reference)
2nd quartile (2.87–3.12)
0.912
(0.697–1.193)
0.500
3rd quartile (3.12–3.40)
1.065
(0.822–1.380)
0.634
4th quartile (≥3.40)
0.966
(0.740–1.260)
0.797
T3 (pg/mL)
(40 ~ 59 age subjects)
1st quartile (<2.87)
1 (reference)
2nd quartile (2.87–3.12)
1.071
(0.895–1.282)
0.452
3rd quartile (3.12–3.40)
1.153
(0.962–1.381)
0.123
4th quartile (≥3.40)
1.056
(0.871–1.280)
0.581
T3 (pg/mL)
(60 or older age subjects)
1st quartile (<2.87)
1 (reference)
2nd quartile (2.87–3.12)
0.823
(0.467–1.450)
0.500
3rd quartile (3.12–3.40)
1.200
(0.695–2.070)
0.514
4th quartile (≥3.40)
1.086
(0.565–2.087)
0.804
Adjusted for age, sex, diabetes, hypertension, hyperlipidaemia, and current smoker. Characteristics of disease (hypothyroidism, hyperthyroidism, nodular cyst, hormone treatment) include both medical history review and currently diagnosed disease. Diabetes is diagnosed as fasting plasma glucose (126 mg/dL). Hypertension is diagnosed as a systolic blood , a diastolic blood , or current use of antihypertensive drugs. Hyperlipidaemia is diagnosed as abnormally elevated serum level of any or all lipids and/or lipoproteins. Multivariate logistic regression analysis.
