Journal of Ophthalmology / 2017 / Article / Tab 6

Research Article

Glaucomatous Optic Nerve Changes and Thyroid Dysfunction in an Urban South Korean Population

Table 6

Adjusted odds ratio and 95% confidence intervals of glaucoma stratified by thyroid function.

VariablesOdds ratio95% confidence interval value

Age1.029(1.024–1.035)<0.001
Sex (male)1.783(1.583–2.007)<0.001
Diabetes1.087(0.878–1.345)0.445
Hypertension1.860(1.632–21,192)<0.001
Hyperlipidaemia0.963(0.850–1.090)0.547
Current smoker0.878(0.781–0.988)0.031

T3 (pg/mL)(All subjects)
 1st quartile (<2.87)1 (reference)
 2nd quartile (2.87–3.12)1.008(0.873–1.164)0.915
 3rd quartile (3.12–3.40)1.134(0.984–1.306)0.082
 4th quartile (≥3.40)1.036(0.892–1.203)0.646

T3 (pg/mL)(20 ~ 39 age subjects)
 1st quartile (<2.87)1 (reference)
 2nd quartile (2.87–3.12)0.912(0.697–1.193)0.500
 3rd quartile (3.12–3.40)1.065(0.822–1.380)0.634
 4th quartile (≥3.40)0.966(0.740–1.260)0.797

T3 (pg/mL)(40 ~ 59 age subjects)
 1st quartile (<2.87)1 (reference)
 2nd quartile (2.87–3.12)1.071(0.895–1.282)0.452
 3rd quartile (3.12–3.40)1.153(0.962–1.381)0.123
 4th quartile (≥3.40)1.056(0.871–1.280)0.581

T3 (pg/mL)(60 or older age subjects)
 1st quartile (<2.87)1 (reference)
 2nd quartile (2.87–3.12)0.823(0.467–1.450)0.500
 3rd quartile (3.12–3.40)1.200(0.695–2.070)0.514
 4th quartile (≥3.40)1.086(0.565–2.087)0.804

Adjusted for age, sex, diabetes, hypertension, hyperlipidaemia, and current smoker.
Characteristics of disease (hypothyroidism, hyperthyroidism, nodular cyst, hormone treatment) include both medical history review and currently diagnosed disease.
Diabetes is diagnosed as fasting plasma glucose (126 mg/dL).
Hypertension is diagnosed as a systolic blood , a diastolic blood , or current use of antihypertensive drugs.
Hyperlipidaemia is diagnosed as abnormally elevated serum level of any or all lipids and/or lipoproteins.
Multivariate logistic regression analysis.

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