Diagnostic Ability of Retinal Nerve Fiber Layer Thickness Deviation Map for Localized and Diffuse Retinal Nerve Fiber Layer Defects

Table 1

Demographic characteristics of study subjects.

	Normal	Glaucoma		Localized RNFL defects	Diffuse RNFL defects
	165	139		62	71
Age (yrs)	56.9 ± 10.8	57.1 ± 13.6	0.849	55.7 ± 13.2	58.0 ± 14.0	0.340
Gender (male : female)	88 : 77	78 : 61	0.711^†	33 : 29	41 : 30	0.727^†
Intraocular pressure (mmHg)	14.9 ± 2.7	14.8 ± 3.4	0.885	15.2 ± 3.5	14.5 ± 3.0	0.219
Signal strength	8.26 ± 0.93	8.06 ± 1.04	0.073	8.15 ± 1.17	7.83 ± 0.90	0.233
Refractive error (diopters)	−0.55 ± 1.48	−0.89 ± 2.08	0.107	−1.19 ± 2.41	−0.71 ± 1.69	0.185
MD (dB)	−0.66 ± 1.31	−5.26 ± 5.12	<0.001	−3.06 ± 3.47	−7.56 ± 5.47	<0.001
(MD ≥ −6 : MD < −6)	—	91 : 48	—	49 : 13	36 : 35	0.001^†
PSD (dB)	1.89 ± 1.01	5.14 ± 4.22	<0.001	2.95 ± 2.18	7.35 ± 4.55	<0.001
Disc area (mm^2)	2.14 ± 0.40	2.07 ± 0.43	0.126	2.04 ± 0.42	2.10 ± 0.45	0.466
Rim area (mm^2)	1.32 ± 0.24	0.92 ± 0.26	<0.001	1.05 ± 0.25	0.79 ± 0.19	<0.001

Independent t-test.
^†Chi-squared test.
RNFL: retinal nerve fiber layer; MD: mean deviation; PSD: pattern standard deviation.